Preprandial refers to the period before eating a meal, when blood glucose levels are typically lowest. It is a critical time for glucose metabolism, as it allows the body to use up any excess glucose before consuming more. Understanding preprandial glucose levels is crucial for managing diabetes and other glucose metabolism disorders, as it helps determine appropriate insulin dosing and meal planning. Monitoring and managing preprandial glucose levels involves regular blood glucose testing, lifestyle modifications, and potentially medication or other interventions.